The Binding of Isaac: Afterbirth is a dark fantasy game about a young woman who must find a way to escape from the basement of her house and find help for her family. It's a great adventure game with very few "quest" type moments, instead you play as an orphaned child looking for your life saving. In many ways, The Binding of Isaac: Afterbirth is a straightforward, unpretentious game of escapism.
Isaac is a small baby with no memory of his past lives and so must survive in the world he's been thrust into. The story is simple: the evil is basically evil and their followers are unambiguously good, but there's more to this story than meets the eye.
This game has had many criticisms over its lifespan, one of which is that it is incredibly hard to tell whether Isaac will die or not. The Binding of Isaac is not a game where dying gives you infinite time, but in some cut-scenes Isaac will wake up and be able to go back to the scene where he died. As a result, players can become frustrated at times because they have to replay whole sections of the game just to see what happens next.
However, the game also doesn't let you get too far ahead of the story, so if you're not interested in playing as Isaac and saving the world, then I'd recommend giving up on this game entirely. Isaac is a unique character, and the fact that the story is so straight-forward means that it's hard for someone like you to empathise with him, so there's no need to worry too much if you don't like Isaac, and in many cases playing as the character is the only way to experience the full game.
The Binding of Isaac: Afterbirth is still an interesting game, with a great story, good graphics, and great sound effects. However, it's not a game that anyone should ignore for the sake of feeling bad about Isaac not being playable anymore.
The Binding of Isaac: Afterbirth is a great game that doesn't have many flaws, but that doesn't mean that you can't enjoy it as well. Overall, it's a fantastic adventure with a good story and great gameplay!
This game starts with Isaac walking around a hospital and then the camera pans across to reveal that he's been infected with the "Purple Worm", which can cause the game's main character to change parts of their bodies, such as Isaac turning into a worm. From here you move to other areas, including a cave where you kill more worms and eventually end up in an empty hospital room.
Now the game moves to its final boss, The Queen, who resembles The Big Daddy in terms of how she attacks. She's tough, though, and you'll need to use a lot of ranged weapons in order to take her down in the end.